Editorial Board, iii
Contributors, v
Introduction, xiii
By Gregory H. Branham, Jeffrey S. Dover, Shilpi Khetarpal, Smita R. Ramanadham, and Allan E. Wulc
Preface, xv
xxx
Role of Platelet-Rich Plasma and the Science Behind Its Mechanism of Action: Its Many Uses Including Rejuvenation and Hair Growth, 1
By Nina Semsarzadeh and Shilpi Khetarpal
Introduction: nature of the problem, 1
Platelet-rich plasma, 2
Mechanism of Action, 2
Preparation and Technique, 2
Preprocedure Planning and Safety, 3
Clinical outcomes in androgenetic alopecia, 4
Clinical outcomes in alopecia areata, 6
Other applications in cosmetic dermatology, 8
Summary, 10
Conflict of interest, 11
Disclosure, 11
Therapies for Acne Scarring, 15
By Julia Stiegler and Mara Weinstein
Background, 15
Noninvasive therapies, 16
Retinoids, 16
Chemical Peels, 16
Trichloroacetic acid chemical reconstruction of skin scars, 16
Invasive therapies, 17
Subcision, 17
Dermal Fillers, 17
Punch Techniques, 17
Microneedling, 18
Platelet-Rich plasma, 19
Lasers and energy-based therapies, 19
Ablative Lasers, 19
Fractional Lasers, 20
Hybrid Fractional Laser, 20
Other Lasers, 20
Radiofrequency Microneedling, 20
Combination Techniques, 21
Summary, 22
Disclosure, 22
Radiofrequency Microneedling, 25
By Girish (Gilly) Munavalli, James Childs, and Edward Victor Ross
Video content accompanies this article at http://www.advancesincosmeticsurgery.com.
Radiofrequency background and introduction, 25
Radiofrequency microneedling thermodynamics, 26
The physics of microneedles, 27
Use of microneedle tips, 28
Insulated versus uninsulated needles, 28
Microneedle injury profile and tip and needle design, 29
Control of power delivery, 30
Explanation of the resistance curve, 31
Clinical applications, 31
Patient Selection and Planning, 31
Disclosure, 37
Plasma Energy Skin Rejuvenation, 39
By Richard D. Gentile
Introduction, 39
Energy-based skin rejuvenation, 40
Methods of energy-based skin rejuvenation, 40
Principles of laser and energy-based devices for skin rejuvenation, 41
History and evolution of plasma-based skin rejuvenation, 42
Comparison of energy load, pulsed with continuous, 44
Fractionating Renuvion helium plasma energies, 44
Helium plasma (Renuvion) skin rejuvenation continuous method—the procedure, 45
Indications, 45
Helium plasma (Renuvion) skin rejuvenation—pulsed technique, 47
Helium plasma (Renuvion) skin rejuvenation—fractionated technique, 50
Summary, 50
Disclosure, 50
Laser-Assisted Drug Delivery, 51
By Omer Ibrahim, Sara Hogan, and Jeffrey S. Dover
Video content accompanies this article at http://www.advancesincosmeticsurgery.com.
Introduction: nature of the problem, 51
Surgical technique, 52
Preoperative Planning, 52
Preparation and Patient Positioning, 53
Procedural Approach: Step 1, Step 2, and so Forth (Including Video), 53
Immediate Postprocedural Care, 53
Clinical results in the literature, 54
Dysplasia, 54
Scars, 54
Anesthetics, 54
Aesthetics, 55
Potential risks and complications, 55
Local Cutaneous Reactions, 55
Systemic Reactions and Toxicity, 56
Summary, 56
Disclosure, 56
Nonsurgical Rhinoplasty, 61
By Zachary Farhood, Haley N. Bray, Yusuf M. Agamawi, and Scott G. Walen
Introduction, 61
Anatomy, 61
Patient selection, 62
Injection materials, 62
Techniques, 63
Basic Principles, 63
Nasal Subsites, 64
Complications, 64
Outcomes, 66
Summary, 66
Disclosure, 66
Incisionless Otoplasty, 69
By Andres Gantous
Video content accompanies this article at http://www.advancesincosmeticsurgery.com.
History, 69
Incidence and etiology, 70
Impact of prominent ears, 70
Nonsurgical treatment of prominauris, 70
Surgical technique, 70
Postoperative care, 75
Discussion, 75
Disclosure, 75
Deoxycholic Acid in Aesthetic Medicine, 77
By Jacqueline Watchmaker, Daniel J. Callaghan III, and Jeffrey S. Dover
Introduction, 77
History of deoxycholic acid in aesthetic medicine, 77
Mechanism of action of deoxycholic acid, 78
Use of deoxycholic acid in submental fat contouring, 78
Submental Fat and Quality of Life, 78
REFINE-1 and REFINE-2, 78
Best Practices for Use of Deoxycholic Acid in Submental Fat Reduction, 78
Dosage, Frequency, Injection Technique, and Postprocedure Evaluation, 79
Adverse Events and Safety Considerations, 79
Patient Experience and Patient-Reported Outcomes, 80
Off-label use of deoxycholic acid, 80
Infraorbital Fat Pads, 80
Xanthelasma, 80
Jowls, 80
Upper and Lateral Back Fat (Bra-Line Fat), 84
Thighs and Lower Abdominal Fat, 84
Piezogenic Pedal Papules, 84
Lipomas, 84
Involuted Hemangiomas (Fibrofatty Tissue), 84
Paradoxic Adipose Hyperplasia Secondary to Cryolipolysis, 85
Deoxycholic acid versus other fat reduction methods, 85
Summary, 85
Disclosure, 86
Perioral Rejuvenation, 89
By Farah Moustafa, Omer Ibrahim, and Jeffrey S. Dover
Introduction: nature of the problem, 89
Surgical technique, 90
Preoperative Planning, 90
Preparation and Patient Positioning, 90
Procedural approach, 91
Neuromodulators, 91
Soft Tissue Filler, 92
Lasers, 93
Summary, 96
Facial Contouring with Neuromodulators, 99
By Kerry Heitmiller, Christina Ring, and Nazanin Saedi
Masseter muscle hypertrophy, 99
Introduction, 99
Clinical Outcomes, 100
Procedural Logistics: Injection Technique, Dose, Frequency, and Type of Botulinum Toxin, 100
Patient Selection, 101
Side Effects, 102
Platysmal bands, 102
Introduction, 102
Clinical Outcomes, 103
Procedural Logistics: Injection Technique, Dose, Frequency, and Type of Botulinum Toxin, 103
Patient Selection, 105
Side Effects, 105
Summary, 105
Disclosure, 106
Forehead Rejuvenation: A Nonsurgical Approach, 109
By Sara Hogan, Katie Beleznay, and Jean Carruthers
Introduction, 109
Anatomy, 110
Patient evaluation, 112
Neuromodulators, 112
Soft tissue filler augmentation, 114
Preprocedure, 114
Procedure, 114
Post-procedure, 114
Complications, 114
Laser, 119
Energy devices, 119
Thread lifts, 119
Summary, 119
Disclosure, 120
New Toxins and Fillers on the Horizon: Implications for Both Patients and Practices, 123
By Jessica G. Labadie, Jeffrey S. Dover, and Murad Alam
Introduction, 123
Neurotoxins, 123
Neurotoxins: Background, 123
Neurotoxins: The Market, 124
US Food and Drug Administrationâ Approved Neurotoxins, 124
New Neurotoxins on the Horizon (Clinical Trials Currently Under Way), 126
Fillers, 128
Dermal Fillers: Background, 128
Dermal Fillers: The Market, 128
New Fillers on the Horizon, 128
New techniques and indications on the horizon, 130
Botulinum Toxin and Dermal Fillers, 130
Botulinum Toxin and Laser/Light Modalities, 130
Microbotox, 132
Filler and Melanoma, 132
Summary, 132
Disclosure, 132
Body Dysmorphic Disorder and the Cosmetic Patient, 135
By Sara Hogan, Neelam Vashi, Jeffrey S. Dover, and Kenneth A. Arnd
Introduction, 135
Defining body dysmorphic disorder, 136
Evaluation of the patient with body dysmorphia, 136
Treating the body dysmorphic patient, 138
Body dysmorphic disorder in the cosmetic setting, 138
Treatment, 138
Summary, 140
Nonsurgical Vaginal Treatment with Lasers and Energy-Based Devices, 143
By Macrene Alexiades
Introduction, 143
Clinical signs and symptoms, 144
Vaginal Atrophy, 144
Vulvovaginal Laxity, 144
Stress Urinary Incontinence, 144
Genitourinary Syndrome of Menopause, 144
Histopathology, 144
Pathogenesis, 144
Treatment, 144
Lasers and Energy-Based Devices, 145
Histologic results, 146
Fractional Lasers, 146
Radiofrequency Devices, 147
Clinical studies, 147
Fractional CO2 Laser, 147
Fractional Er:YAG Laser, 149
Hybrid Fractional Laser, 149
Radiofrequency, 149
At-home Devices, 150
Safety, 150
Summary, 150
Disclosure, 151
Hyperhidrosis: A Review and Treatment Options, 155
By Kara Hoverson and Prasanthi Kandula
Introduction, 155
Topical agents, 155
Antiperspirants, 155
Topical Anticholinergics, 156
Systemic agents, 156
Systemic Agents: Anticholinergics and Clonidine, 156
Procedures, 157
Iontophoresis, 157
Botulinum Toxin, 158
Microwave Thermolysis, 158
Suction Curettage, 159
Sympathectomy, 160
Emerging therapy, 160
Disclosure, 160
Update on Thread-Lifting, 165
By Leah K. Spring and Daniel J. Callaghan III
Introduction, 165
Poly-L-Lactic Acid Threads (Silhouette Soft Sutures), 166
Procedure and technique, 167
Preoperative Planning and Patient Selection, 167
Preparation and Patient Positioning, 168
Procedural Approach, 168
Immediate Postprocedural Care, 168
Complications, 168
Immediate Postprocedural Complications, 169
Thread-Related Complications, 169
Delayed Complications, 169
Complication prevention, 169
Complication treatment, 169
Discussion, 170
Commoditization of the Procedure, 170
Lack of Evidence, 170
Summary, 170
Disclosure, 170
Advances in Skin Tightening with Liposculpture: Plasma Technology Versus Radiofrequency, 173
By Ryan Neinstein and Christopher D. Funderburk
Video content accompanies this article at http://www.advancesincosmeticsurgery.com.
Preoperative assessment, 174
Medical history, 174
Physical examination, 175
Informed consent and photography, 175
Wetting solutions, 175
Operative considerations, 175
Cannulas, 175
Adjunctive Liposuction Technology/Techniques, 176
Postoperative care, 177
Complications, 177
Local, 177
Systemic Complications, 177
A comparison of the BodyTite platform and the Renuvion/J-plasma system, 177
BodyTite, 177
Renuvion/J-Plasma, 183
Summary, 185
Disclosure, 186
Deep Neck Lifting: An Introduction to Comprehensive Management of the Deep Fat, Perihyoid Fascia, Digastric Muscles, and Submandibular Glands, 189
By Thomas Gerald O’Daniel and Swapnil D. Kachare
Video content accompanies this article at http://www.advancesincosmeticsurgery.com.
Introduction, 189
Relevant anatomy, 191
Platysma, 192
Deep fat, 192
Perihyoid fascia, 192
Digastric muscle, 192
Submandibular gland, 192
Options for neck lifting, 193
Isolated Neck Lift, 193
Combined Neck Lift and Facelift, 193
Evaluation and indications for managing deep neck structures, 193
Submental Triangle, 193
Perioperative considerations, 195
Anesthesia, 195
Intraoperative, 196
Surgical planning, 196
Incisions, 196
Skin Flap Creation, 197
Supraplatysmal fat management, 198
Submental triangle exposure, 198
Management of the deep fat, 200
Management of perihyoid fascia, 201
Management of the digastric muscles, 201
Management of submandibular glands, 203
Management of platysma, 205
Postoperative management, 206
Physical activity, 207
Dietary restrictions, 207
Summary, 208
Disclosure, 208
The Nanofat Method for Mechanical Stromal Vascular Fraction Isolation: Principle and Clinical Application, 209
By Alexis Verpaele, Patrick Tonnard, and Mohammad Ghiasloo
Video content accompanies this article at http://www.advancesincosmeticsurgery.com.
Introduction, 209
Indications, 210
Surgical procedure, 210
Clinical indications and cases, 211
Discussion, 214
Disclosure, 215
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